Virulence factors and quorum sensing as targets of new therapeutic options by plant-derived compounds against bacterial infections caused by human and animal pathogens

The emergence of antibiotic-resistant bacteria and hospital-acquired bacterial infection has become rampant due to antibiotic overuse. Virulence factors are secondary growth important in their pathogenesis, therefore, new antimicrobial therapies inhibit virulence becoming strategies against resistance. Here, we focus on anti-virulence that act through anti-quorum sensing the subsequent clearance by compounds, especially active herbal extracts. These quorum systems based toxins, biofilms, efflux pumps, bioactive compounds isolated from medicinal plants can treat pathologies. Ideally, bacteria. Hence, inhibition could reduce pathogenesis. Furthermore, be developed as novel treatments for infection. Therefore, this narrative review aims discuss acting preserved targets treating plant-derived compounds. Keywords: resistance, pathogens, phytochemicals, system, factors.